Search on: FATTY ACID SYNTHASE, TYPE I 
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Descriptor English:   Fatty Acid Synthase, Type I 
Descriptor Spanish:   Acido Graso Sintasa Tipo I 
Descriptor Portuguese:   Ácido Graxo Sintase Tipo I 
Tree Number:   D08.811.277.352.897.387.100
D08.811.520.241.300.287.099
D08.811.641.758
D08.811.682.047.820.196.500.099
D08.811.913.050.134.029.500.100
D08.811.913.050.170.500.100
Definition English:   Animal form of fatty acid synthase which is encoded by a single gene and consists of seven catalytic domains and is functional as a homodimer. It is overexpressed in some NEOPLASMS and is a target in humans of some ANTINEOPLASTIC AGENTS and some ANTI-OBESITY AGENTS. 
History Note English:   2014(2008) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52720 
Unique Identifier:   D054890 

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